Is the Yamaha R6 reliable for high mileage?

The Yamaha R6 is a high performance machine, but there is still a lot of talk about the longevity and reliability of the bike when it's used a lot. R6s are ridden by some riders to tens of thousands of miles without problems, while some report more frequent maintenance needs. This is where riding style, maintenance habits, how much street vs track riding you do and more come into play. The debate rages about whether the R6's high revving engine is as reliable over time as other supersports, and if some model years are more reliable than others. Regular maintenance is often discussed in the conversation along with the cost of ownership over the years, and whether the R6 will make a good long term mileage bike.